Causes
A tumour (almost always benign) in the pituitary gland or, less commonly, in the adrenal glands. It can also be caused by prolonged use of corticosteroids (iatrogenic Cushing's).
Diagnosis
Blood tests and specific hormone tests, abdominal ultrasound.
Treatment
Lifelong treatment with medication that controls cortisol production, with regular monitoring. In corticosteroid-induced Cushing's, gradual withdrawal of the drug. Quality of life improves markedly.
Prevention
The tumour-related form cannot be prevented. Avoid prolonged and unnecessary use of corticosteroids.

