Causes
A malignant tumour whose cause is not fully understood. Large and giant breeds (Great Dane, St Bernard, Greyhound, Rottweiler) are at much higher risk. It usually affects the limbs.
Diagnosis
X-rays plus a biopsy to confirm. Staging tests (chest) because it metastasises early, mainly to the lungs.
Treatment
Pain management (it is very painful), often amputation of the limb plus chemotherapy. The prognosis is guarded because of the tendency to metastasise. Pain control and quality of life are the priorities.
Prevention
Not preventable. Early detection of persistent lameness allows earlier intervention.

